The killzone is spheroidal so treestand angles will cut your margin for error pretty good as you move forward the leg.
The "V" is deadly but I do not at all advocate treestand bowhunters to aim there (1-2") in front of leg,
I've been well served by 1" behind leg on broadside angle and adjust more rearwardly on quartering a away (between same side and offside legs)from treestands.
Other issues are tracking conditions to be considered.
Shoulders shots also create so many tracking dilemmas as often the blood with be aerated but it isn't lung blood.It's the great masquerader and is probally the single shot in bowhunting that gives wound loss.
More issues
1.Scapula/bone is less forgiving and do a good job of thwarting arrow penetration 2. One lung deer are pushed to early due to the falsely reading blood sign. 3. The spine lowers pretty much as you move forward the leg as well and many "shoulder" shots are actually shots above the spine (as much as 6 inches from top of back in relation) ie. "the void"
All in all,your not gonna make a living playing it tight to the leg from elevation........hope this helps.
From a treestand the scapula will close the 4" down to only three inches on the right side.Also the left side has liver to bail out in and even the worst case scenario of paunch/intestines.
Aiming straight up the leg is risky and why my aimpoint is behind that spot.I would swap a longer blood trail versus a scapula hit anyday.
Scapulas move from impact and on bow sound ....they will ruin your year of hard work......dodge them.
I hate gut/paunch hits like the next guy but give me them 100 fold over a scapula hit.
With the paunch hit you know exactly what your dealing with and how to handle it.The scapula hit is a teaser that may cause you to push the trail too much losing your one lunger (if that)
The Midwest deer jump some but do not belly flop like their southern brothers.
Coues don't even jump as much southeastern whitetails
The good thing about string jump (if their is such a thing) is the deer move forward helping you to stay away from the scapula.
I shot a doe in the offside ham once from her flinching at 15 yards........pure luck
Any angle will push the shot forward with the oft repeated advice to aim for the opposite leg.
Likewise many a deer has lived because people were lectured to stay away from anything frontal.
Couple of reasons IMHO is that one equipment has gotten soooo much better and overall better accuracy on average.
This being said I have moved my aim point closer to the crease of the leg.