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Prenatal THC Exposure
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Contributors to this thread:
Annony Mouse 04-Jan-19
70lbdraw 04-Jan-19
BIG BEAR 04-Jan-19
LINK 04-Jan-19
From: Annony Mouse
04-Jan-19
The ever growing expansion to legalize marijuana may have much regrets in the future. Article is from the latest issue of The Scientist. For those of you in parenting age (or have children producing grandchildren), article is worth a read.

Prenatal Exposure to Cannabis Affects the Developing Brain

Children born to moms who smoked or ingested marijuana during pregnancy suffer higher rates of depression, hyperactivity, and inattention.

A few bits from the article:

"...When marijuana is ingested or smoked during pregnancy, exogenous cannabinoids enter the blood and cross easily through the placental barrier due to their highly lipophilic nature. Pairing this ready availability with slow pharmacokinetics—active metabolites continue circulating for up to five days depending on dosage and frequency of use—fetal exposure to the active compounds in cannabis is both efficient and prolonged. It should therefore be expected that this exposure can profoundly influence the development of the ECS..."

"To date, the three largest longitudinal studies of the children of women who smoked marijuana once a week or more during their pregnancies have identified remarkably consistent outcomes during early development and through young adulthood. In infants, these include increased impulsivity, hyperactivity, and delinquent behaviors, as well as memory dysfunction and decreased IQ scores. During adolescence and early adulthood, fetal cannabis exposure has been linked to persistent reduction in memory and concentration, higher rates of drug use, and an increased incidence of hyperactivity, signs of depression, and psychotic and schizophrenic-like symptoms. These mental health issues are further evidenced by increased reports from both parents and schoolteachers of problematic behavior and delinquency in cannabis-exposed kids..."

"...A Lifetime of Consequences?

Large-scale, longitudinal studies of humans whose mothers smoked marijuana once or more per week and experimental work on rodents exposed to cannabinoids in utero have yielded remarkably consistent intellectual and behavioral correlates of fetal exposure to this drug. Some exposed individuals exhibit deficits in memory, cognition, and measures of sociability. These aberrations appear during infancy and persist through adulthood and are tied to changes in the expression of multiple gene families, as well as more global measures of brain responsiveness and plasticity. Researchers currently consider these perturbations to be mediated by changes to the endocannabinoid system caused by the active compounds in cannabis..."

Because of its federal drug status, it has been difficult to do necessary research about the effects of the various kinds of THC and consequences of usage. Regulated pharmaceuticals still have occasionally been demonstrated to have unexpected or negative effects long after they have been licensed. Yet marijuana of unknown composition and concentration (with little actual research) is being touted as the "next great thing" in pharmacology.

Act in haste...repent in leisure.

From: 70lbdraw
04-Jan-19
"Children born to moms who smoked or ingested marijuana during pregnancy suffer higher rates of depression, hyperactivity, and inattention."

Lol! I suffer from all 3 of those, and my mom never even smoked a cigarette!

From: BIG BEAR
04-Jan-19
Anyone dumb enough to smoke weed when they’re pregnant was dumb enough to do it before it was legal here Jack.

From: LINK
04-Jan-19
My wife just had our fourth. She would get on a webpage called The Bump. It’s amazing how many woman on there would talk about using marijuana and drinking while pregnant. My wife won’t hardly drink caffeinated coffee while pregnant, lol.

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