Moultrie Products
Cancer breakthrough
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Contributors to this thread:
Spike Bull 04-Jan-19
JTV 04-Jan-19
Will 04-Jan-19
JTV 04-Jan-19
Annony Mouse 04-Jan-19
HA/KS 04-Jan-19
Spike Bull 04-Jan-19
JTV 04-Jan-19
DL 04-Jan-19
sleepyhunter 04-Jan-19
Spike Bull 05-Jan-19
04-Jan-19
Cut and paste, this addy is way too long for Bowsite application.

http://unitedwithisrael.org/alpha-radiation-startup-eliminates-70-of-cancerous-tumors/?utm_source=MadMimi&utm_medium=email&utm_content=Israeli+Breakthrough+Eliminates+70_+of+Cancerous+Tumors%3B+%27No+More+Luxuries%27+for+Terror+Prisoners%3B+Abbas+Party+Seeks+Violent+Future&utm_campaign=20190103_m149075558_Israeli+Breakthrough+Eliminates+70_+of+Cancerous+Tumors%3B+%27No+More+Luxuries%27+for+Terror+Prisoners%3B+Abbas+Party+Seeks+Violent+Future&utm_term=Israeli+Breakthrough+Eliminates+70_25+of+Cancerous+Tumors

From: JTV
04-Jan-19
it runs off the page ....lol .........

From: Will
04-Jan-19
Interesting stuff Spike - sure as heck hope that the trials continue and it's affirmed and can become a great tool in the fight against that evil disease.

From: JTV
04-Jan-19
WOW, I hope this has abundant uses and becomes popular here in the US ....

From: Annony Mouse
04-Jan-19
From: HA/KS
04-Jan-19

HA/KS's Link
Spike, if you just delete everything after the ? on those long URLs, they work fine.

04-Jan-19
Thanks, all.

I pray it works out. They have permits to set up a manufacturing facility next door in Massachusetts.

04-Jan-19
I cannot get this to open.

Spike, is this a drug that has been approved? Can you please give a couple sentence summary? Thanks.

From: JTV
04-Jan-19
for you HfW ..........

tumors.

By Brian Blum, ISRAEL21c

A breakthrough Israeli technology that eliminates cancerous tumors in 70 percent of patients was nearly lost in bureaucracy and university politics.

Fifteen years ago, Professors Yona Keisari and Itzhak Kelson of Tel Aviv University discovered a way to use alpha radiation to zap tumors. Their approach was revolutionary – alpha radiation is so powerful it can snap both strands of a cancer cell’s DNA, but it won’t harm surrounding healthy tissue as other types of radiation do.

However, alpha radiation can’t travel more than about 50 microns (1/20 of a millimeter) inside human tissue. Treating a tumor of, say, 5cm would require hundreds of thousands of alpha particles – a seeming impossibility.

Keisari and Kelson discovered that, when delivered via a particular isotope of the element radium, alpha radiation can travel as far as 3mm. The isotope, Radium 224, releases atoms that diffuse inside a tumor and then emit their own alpha particles. This approach requires far fewer alpha particles to kill a tumor.

The professors and Tel Aviv University patented the technology in 2003. More research was conducted and 12 peer-reviewed papers were published. But squabbling between the various stakeholders over the intellectual property kept their breakthrough in limbo until 2015 when Uzi Sofer was recruited to sort things out.

Sofer had an impressive track record in medical technology. He previously cofounded and served as CEO of Brainsway, which develops treatments using transcranial magnetic stimulation (TMS) for depression, PTSD, OCD and other brain disorders and addictions. The company grew under his leadership from two to 70 employees.

Realizing what the professors had, Sofer formed a new company – Alpha Tau (the “Tau” stands for Tel Aviv University) – to further develop the technology. Earlier this year Alpha Tau raised $29 million from Shavit Capital, Medison Ventures and OurCrowd.

Stimulates Immune System Alpha Tau is the only company to use alpha radiation to zap tumors. All other types of brachytherapy (where a sealed radiation source is placed inside or next to the area requiring treatment) use beta or gamma radiation.

“But that only causes a single-strand break in the DNA, from which the cell can recover,” Sofer explains. “And it’s not as focused. As a result, it causes a lot of side effects and destroys healthy tissue.”

When the healthy tissue around the tumor is not destroyed along with the cancer, the immune system is stimulated to recognize and attack the same type of tumors elsewhere in the body. These kinds of metastases are the cause of death for 85% of cancer patients.

“We believe that DaRT technology has tremendous clinical value not only in destroying the tumor but preventing cancer from spreading to other organs,” Sofer says.

Clinical Trials Thousands of animal studies have been done on the company’s Alpha DaRT (“Diffusing Alpha-Emitters Radiation Therapy”) technology.

The first human trials of Alpha DaRT have been taking place in Israel and Italy for squamous cell carcinoma (SCC) tumors, a form of skin and oral cancer; and in Israel, Italy, New York and Montreal for congenital melanocytic nevus (CMN).

Clinical trials of DaRT planned for 2019 will take place in France (CMN), Montreal and New York (pancreatic and prostate cancer), Russia (breast cancer) and Israel (prostate cancer). Additional trials will later be initiated for more than 20 other indications – such as vulvar, cervical, renal and colon cancer – at medical centers in more than 25 countries.

“We can treat any kind of solid tumor,” Sofer tells ISRAEL21c, “including cancers where there is no other chance and this is a patient’s last chance to live.”

Pancreatic cancer, for example, today has no cure; patients usually die within five years of diagnosis. Alpha Tau’s DaRT “seeds” may be able to flip that prognosis.

“In our SCC studies, we were able to eliminate more than 70 percent of the tumors entirely and to cause shrinkage of 100 percent of the tumors,” Sofer says. “Encouraged by these promising results, we hope to eliminate pancreatic tumors as well or to shrink them so that it will be possible to remove them surgically.”

Personalized Treatment Kits Despite the power of alpha radiation, it’s actually safer than conventional beta or gamma treatments.

“You don’t need so much radioactivity to get the same effect,” Sofer explains. “We can ship our treatment kit to hospitals almost in regular boxes. Patients can be treated in an outpatient setting with no radioactive shielding.”

After less than a week, 50% of the alpha radiation will already be gone from the body. In two weeks, there will be no radioactivity left at all.

However, once a DaRT kit is assembled (for example, a patient with breast cancer might need 12 needle applicators with 6 DaRT seeds in each) it must be sent to the treatment facility fast.

“If for some reason a patient doesn’t come on time, the next day you’ll need to put the whole kit in the trash,” Sofer says.

Because of DaRT’s fast decay, Alpha Tau will need to build production facilities close to the main treatment centers. The first one is already working in Israel. The company has received approval to build a facility in Massachusetts. The third will be in Japan with a fourth in Europe, Sofer says.

Under Sofer’s leadership, Alpha Tau now has 26 on staff in Israel, including the professors who invented the core technology. Following clinical testing, Sofer hopes Alpha DaRT will receive its European Union approval in 2020 with the US and Japan coming in 2022.

“We are already saving lives in the trials,” he says. “It’s amazing to see patients who have been told their life expectancy is in weeks get treatment under local anesthesia and, 60 days out, they’re clear, they have no evidence of any tumors. I’ve been in this business for a while, but this is the best.”

04-Jan-19
Thanks Jeff!

Wow, awesome!!

From: DL
04-Jan-19
My brother has had cancer for around 20 years. First he lost a kidney and a section of his vena cava. Then after several years of no cancer it came Back with a vegence. Renal Cell Carcinoma. It showed up with a lot of tumors in his lungs. Dr said get your life in order you have about 9 months to live. So he headed to Stanford University med center. He agreed to go on an experimental drug program. He had the largest tumors removed and the lower lobe of one lung. The drug shrunk the remains tumors down to a few millimeters. That was about 15 years ago The sad thing about these drug test programs is some individuals get placebos and will die. Not surprised that Israel is on the cutting edge of this. You can bet any Saudi princes get cancer they will head to Israel before any of their hospitals.

From: sleepyhunter
04-Jan-19
Pancreatic Cancer is what took my Mother. I hope this new technology will come to the USA.

05-Jan-19
There are already many successful alternative treatments available for many cancers but the FDA and big pharma suppress them cruelly. I believe that the FDA will not stand in the way of this one as it will be made within the cancer hierarchy that already exists here.

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